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Amphetamine is known to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit numerous P450 isozymes as well as other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes suggest small inhibition of CYP2D6 by amphetamine and minimal inhibition of CYP1A2, 2D6, and 3A4 by a numbe